Interferon-gamma

The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.

Also Known As:

Interferon, gamma; Immune Interferon; Type II Interferon; Interferon, Type II; Interferon Type II; Interferon, Immune; gamma-Interferon; Interferon gamma (human lymphocyte protein moiety reduced)

Pharmalogical Action Categories:

Antiviral Agents

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Interferons: 39171
        Interferon-gamma: 15725
      - Lymphokines: 811
        Macrophage-Activating Factors: 14
        Interferon-gamma: 15725
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Interferons: 39171
        Interferon-gamma: 15725
      - Lymphokines: 811
        Macrophage-Activating Factors: 14
        Interferon-gamma: 15725
Biological Factors: 2472
- Intercellular Signaling Peptides and Proteins: 29768
  - Cytokines: 164289
    - Interferons: 39171
      - Interferon-gamma: 15725
    - Lymphokines: 811
      - Macrophage-Activating Factors: 14
        Interferon-gamma: 15725

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Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure